临床研究人类视网膜电图暗适应及明适应震荡电位的参数特征.pdfVIP

2011;31(12) 南方医科大学学报（J South Med Univ ） ·2057 · ·临床研究· 人类视网膜电图暗适应及明适应震荡电位的参数特征 银娟萍，雷 博，彭 惠，王 隽，付校楠 重庆医科大学附属第一医院眼科，眼科学重庆市市级重点实验室，重庆市眼科研究所，重庆 400016 摘要：目的为了描述在相同闪光刺激强度下，人类视网膜在不同适应状态下的震荡电位（OPs）特征。方法对正常受试者 行全视野视网膜电图(ERG)检查。然后应用数字滤波技术提取暗适应3.0 和明适应3.0ERG 信号中的震荡电位，并对震荡 电位进行傅里叶频谱分析。分别确定暗适应以及明适应震荡电位的参数（频率峰值、潜伏期、能量）。结果确定了暗适应 2 震荡电位的频率峰值平均值为（125.3±9.93）Hz ，潜伏期平均值为（41.7±3.56）ms ，能量平均值为（9.25±5.55）(μV ·s) ；明适 2 应震荡电位的频率峰值平均值为（79.5±6.79）Hz ，潜伏期平均值为（50.8±5.36）ms ，能量平均值为（3.56±2.18）(μV ·s) 。 分别对暗适应与明适应震荡电位的参数（频率峰值，潜伏期，能量）进行比较，发现均有显著差异（P0.001)。结论与暗适 应震荡电位参数相比较，明适应震荡电位的峰值频率及能量更低、潜伏期更长。 关键词：震荡电位；暗适应；明适应 中图分类号：R774 文献标志码：A 文章编号：1673-4254（2011）12-2057-04 Characteristics of dark-adapted and light-adapted oscillatory potentials in human electroretinogram YIN Juan-ping, LEI Bo, PENG Hui, WANG Jun, FU Xiao-nan Department of Ophthalmology, First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Ophthalmology, Chongqing Eye Institute, Chongqing 400016, China Abstract: Objective To characterize dark-adapted and light-adapted oscillatory potentials (OPs) in human electroretinogram (EGR) elicited by flashing light stimulation of the same intensity. Methods Dark- and light-adapted ERGs of normal eyes were studied. The frequency spectra of the extracted dark-adapted OPs and light-adapted OPs were analyzed by a fast Fourier transform. The peak frequency, latency and total power of the OPs were determined.