醋酸生长抑素与醋酸奥曲肽治疗食管-胃底静脉曲张破裂出血的成本-效果分析.pdfVIP

醋酸生长抑索与醋酸奥曲肤治疗食管一冒底静脉曲张破裂出血的成本一效果分析 颜鲁青飞扬小择，刘 兰(青海省人民医院药割科，西宁市 810007) 中固分类号 R956jR973' .1 文献标识码 C 文章编号 1001-0408(2007)20… 1526… 02 摘 要 目的:评价醋酸生长抑索与西苦酸奥曲欣治疗食管 胃底静脉由张破裂出血的成本 效果。方法:采用回顾性调查方法，对 醋政生长抑索与醋酸奥曲欣治疗 61 例食管…宵底静脉曲张破裂出血的患者进行成本一效采分析。结果:醋酸生长抑索组与腊政奥 曲欣组的总成本分别为 11 141. 00 、 9325.30 元，总有效率分别於183.87% 、 86.67% (P>O.O日，成本吵效果比分别为 13283缘由、 结论:相对于醋政生长抑素，甜酸奥曲肤无论从有效率还是药物经济学角度分析都占优势。 10759.55 0 食营一胃底出血;醋酸生长抑素;醋酸奥曲欣;成本一效果分析 关键词 Somatostatin Acetate/Octretide Acetate for Esophagogastric Variceal Bleeding: Cost - Effectiveness Analysis YAN Luqing ,YANG Xiaoping ,LIU Lan(Dept. of Pharmacy , Qinghai Provincial People' s Hospital ,Xining 810007 ,China) ABSTRACT OB]ECTIVE:To 巳valuate the cost …巳ffectiv巳ness of sornatostatin acetate vs octreotid巳 ac巳tate for esophagogas- tric variceal bleeding(EGVB) .METHODS: By retrospective study ,the cost - effectiveness of somatostatÎn acetate vs. octrec>tide ac日tate in treating 61 patients with EGVB was performed.RESULTS: The total costs for somatostatin acetate group and oc- treotide acetate group were 11 141.00yuan and 9 325. 30yuan ,respectively; the total effective rates were 83.87% and 86.67% , respectively( P > 0.0日， and the cost effectiveness ratÎos were 13283.65 and 10759.55, respectively.CONCLUSION: As cornpared with somatüstatin acetat巴， octreotide acetat巳 is sup巳rior eith巳r in efficacy or in pharrnacoeconornics for EGVB. KEY WORDS Esophagogastric varic巳al bl巴巴ding; Somatostatin acetate; Octreotide ac巳tate;Cost … effectiv巳n巴ss analysis 2.1 成本的确定 肝硬化最严攘的并发症是门脉高压所致的食管 罔躏静 药物经济学成本是实施某…药物治疗方案或其他治疗方 脉曲张破裂出血 (EGVB) ，其病死率高达 30%-50% ，有效抑 案的模个过程中所投入的全部财力资源、物质资源和人力资源 制出血是降低死亡率的关键。醋酸1:.长仰索(德国米奥大药厂，